GTX71753 CaSR / PCAR1 antibody
see related secondary antibodiessee all 18 CaSR / PCAR1 products
25 µg / no delivery possible
Quick Overview
Rabbit anti CaSR / PCAR1
Synonyms
Calcium Sensing Receptor, GPRC2A, PCAR1, FHH, NSHPT, , Extracellular calcium-sensing receptor, Parathyroid Cell calcium-sensing receptor
Product review
Please read our product review about CaSR / PCAR1 : Antibodies to Calcium Sensing Receptor (CaSR).
Product Description
Rabbit anti CaSR / PCAR1 . Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | GTX71753 |
| Swiss Prot. No. | P41180 |
| Quantity | 25 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Calcium Sensing Receptor antibody | |
| Concentration | 1 mg/ml |
| Background | CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al. (2001) and Awata et al. (2001) have identified the binding of filamin-1 to the C-terminal tail of CASR, which may contribute to its localization in caveolae, link it to the actin-based cytoskeleton, and participate in CASR-mediated activation of MAPK. Multiple isoforms for CASR are produced by alternative splicing. CASR has been documented in bone marrow, brain, breast (mostly cancer), colon, kidney, parathyroid, skin, stomach, and thyroid. ESTs have been isolated from normal kidney and gallbladder, in addition to parathyroid cancer libraries. |
| Immunogen | Synthetic peptide - KLH conjugated Swiss Num.: P41180 |
| Format | State: Liquid Purification: Immunogen affinity purified. Purity: Immunogen affinity purified. BufferSystem: Phosphate buffered saline, PH 7.7 containing 0.01% sodium azide |
| Applications | IHC-P |
| Specificity | Human. Others not determined. |
| Storage | Keep as concentrated solution. Store at 4 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX71753 CaSR / PCAR1 '.
