GTX27998 c-Jun peptide antigen
100 µg / no delivery possible
Quick Overview
c-Jun peptide
Product Description
c-Jun peptide
Properties
| Catalog Number | GTX27998 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| c-Jun peptide | |
| Concentration | 0.2 mg/ml |
| Background | The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. c-Jun (previously known as the Fos-binding protein p39) and c-Fos form a complex in the nucleus. AP 1 (activating protein-1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto-oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. |
| Format | State: Liquid - 100 micrograms peptide in 0.5 ml PBS with 0.1%sodium azide and100 micrograms BSA. Purification: n/a Purity: n/a BufferSystem: PBS with 100ug BSA 0.1% sodium azide |
| Applications | BL |
| Storage | Keep as concentrated solution, aliquot and store at 4 |