GTX27993 MAPK8 antigen
see all 14 MAPK8 products
100 µg / no delivery possible
Quick Overview
MAPK8
Synonyms
JNK1 JNK-46 PRKM8 SAPK JNK-1 MAPK-8 Mitogen-activated protein kinase 8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
Product review
Please read our product review about MAPK8: Antibodies to MAP-Kinases.
Product Description
MAPK8 ;Is tested for Flow cytometry (F)
Properties
| Catalog Number | GTX27993 |
| Swiss Prot. No. | P45983 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| JNK1 peptide | |
| Concentration | 0.2 mg/ml |
| Background | MAP kinases consist of several subgroups, including the ERK, JNK, and p38 kinases. The members are regulated by many different extracellular cues ranging from cytokines, growth factors, and neuropeptides. These stimuli activate cell surface receptors to stresses such as cold, heat, osmolarity changes and irradiation. The pathways regulated by the MAPKs control a broad array of cellular responses ranging from survival, cell proliferation, and apoptosis. The MAPKs family is also characterized by their requirement for dual phosphorylation at a conserved threonine and tyrosine residue for enzymatic activation and both must be phosphorylated for full enzymatic activation. The closely related ERK1 (44 kDa) and ERK2 (42 kDa) kinases are characterized by their requirement for dual phosphorylation at a conserved T-E-Y motif. While JNK1 is activated by dual phosphorylation at a T-P-Y motif and p38 is also activated by dual phosphorylation at a T-G-Y motif. |
| Immunogen | Swiss Num.: P45983 |
| Format | State: Liquid - 100 micrograms peptide in 0.5 ml PBS with 0.1%sodium azide and100 micrograms BSA. Purification: n/a Purity: n/a BufferSystem: PBS with 100ug BSA 0.1% sodium azide |
| Applications | BL |
| Storage | Keep as concentrated solution, aliquot and store at 4 |
