GTX23677 p53 (phospho S9) antibody
see related secondary antibodiessee all 270 p53 products
100 µg / no delivery possible
Quick Overview
Rabbit anti p53 (phospho S9)
Product Description
Rabbit anti p53 (phospho S9) , Presentation: Aff - Purified. Product is tested for Enzyme Immunoassay ( E ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Isotype | IgG |
| Catalog Number | GTX23677 |
| Quantity | 100 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| p53 (phospho S9) antibody | |
| Concentration | 0.25 mg/ml |
| Background | The p53 tumor suppressor protein regulates cell cycle progression and cell survival in response to DNA damage and certain other cellular stresses by arresting cell cycle progression or by inducing apoptosis. One of the most important mammalian cell cycle checkpoint proteins is the tumor suppressor p53. In normal, undamaged cells, p53 is rapidly degraded. Treating cells with a variety of DNA damage-inducing agents induces a transient accumulation of p53 protein and activates it as a transcription factor. It is frequently lost or mutated in multiple types of human cancer. Human p53 protein has been shown to be phosphorylated at several N-terminal and C-Terminal sites that in vitro affect site-specific DNA binding and interaction with other cellular and viral proteins. Serines 6, 9, 15, 20, 33, and 37 phosphorylation occurs after cells are exposed either to ionizing radiation or to UV light. Serine 6 and Ser 15 were demonstrated to be one of the strongest and earliest phosphorylated sites in response to DNA damage-induced posttranslational modifications. |
| Immunogen | KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S9 of human P53 |
| Format | State: Liquid Purification: Immunogen affinity purified Purity: Immunogen affinity purified BufferSystem: PBS with 0.02% sodium azide |
| Applications | ELISA, IHC-P, WB |
| Specificity | Human - Not yet tested in other species |
| Storage | Keep as concentrated solution. Store at 4 |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX23677 p53 (phospho S9)'.
