GTX22738 LAP2 [RL29] antibody
see related secondary antibodiessee all 11 LAP2 products
200 µl / no delivery possible
Quick Overview
Hamster anti LAP2 [RL29] RL29
Product Description
Hamster anti LAP2 [RL29] RL29, Presentation: Ig Fraction. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Rat ( Rt ) |
| Presentation | Ig Fraction |
| Host | Hamster |
| Isotype | IgG |
| Clone | RL29 |
| Catalog Number | GTX22738 |
| Quantity | 200 µl |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| LAP2 antibody [RL29] | |
| Background | In eukaryotic cells, the nuclear envelope consists of inner and outer membranes, which define the border between the nucleus and cytoplasm. The inner and outer nuclear membranes are joined by large, supramolecular assemblies called nuclear pore complexes through which various molecules pass into and out of the nucleus. The inner membrane is lined by a filamentous meshwork called the nuclear lamina made up of proteins called lamins. The attachment of the lamins to the inner nuclear membrane appears to occur through their association with 4 related integral membrane proteins called Lamin Associated Polypeptides (LAPs). LAP 1A, 1B & 1C share a high degree of sequence homology while LAP 2 is distinct from the others. LAP 1A & B bind lamins A, C and B1, while LAP 2 binds lamin B1 only. In addition to lamin binding, LAP 2 has been shown to bind to chromosomes. Phosphorylation of LAP 2 during mitosis inhibits binding to both lamins and chromosomes suggesting that LAP 2 plays an important role in nuclear envelope re-assembly. |
| Immunogen | Pore complex-lamina fraction isolated from rat liver nuclear envelopes. |
| Format | State: Liquid Purification: IgG fraction Purity: IgG fraction BufferSystem: PBS with 0.05% sodium azide |
| Applications | IF, IP, WB |
| Specificity | Cross-reacts with Rat. Not yet tested in other species. |
| Storage | Keep as concentrated solution. Store at 4 |
11 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1327B | Hamster IgG (H&L) | ||||||
| Rabbit | Biotin | 1.5 mg / US$ 315 | |||||
| R1327F | Hamster IgG (H&L) | ||||||
| Rabbit | FITC | 1.5 mg / US$ 295 | |||||
| R1327T | Hamster IgG (H&L) | ||||||
| Rabbit | TRITC | 1.5 mg / US$ 295 | |||||
| R1327TR | Hamster IgG (H&L) | ||||||
| Rabbit | Texas Red | 1.5 mg / US$ 315 | |||||
| R1327HRP | Hamster IgG (H&L) | ||||||
| Rabbit | HRP | 1.5 mg / US$ 325 | |||||
| R1327AP | Hamster IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 345 | |||||
| R1437C2 | Hamster IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1437C3 | Hamster IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1437C35 | Hamster IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1437C5 | Hamster IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1437C55 | Hamster IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
Click here to see all secondary antibodies for 'GTX22738 LAP2 [RL29]'.
