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GTX17129  Progesterone Receptor antibody

see related secondary antibodies
see all 76 Progesterone Receptor products
500 µl / no delivery possible
please contact the manufacturer
GeneTex Inc.
San Antonio, TX, USA
www.genetex.com

Quick Overview

Mouse anti Progesterone Receptor hpra 2 + hpra 3

Synonyms

PR, PGR, NR3C3, , Nuclear receptor subfamily 3 group C member 3

Product review
Please read our product review about Progesterone Receptor : Antibodies to Progesterone Receptor.

Product Description

Mouse anti Progesterone Receptor hpra 2 + hpra 3, Presentation: Ig Fraction. Product is tested for Paraffin Sections ( P )

Properties

ApplicationsParaffin Sections ( P )
ReactivityHuman ( Hu )
PresentationIg Fraction
HostMouse
IsotypeIgG1
Clonehpra 2 + hpra 3
Catalog NumberGTX17129
Swiss Prot. No.P06401
Quantity500 µl
Priceno delivery possible
DeliveryEurope only
ManufacturerGeneTex Inc.
DatasheetPDF-Download
http://www.genetex.com/co ...

Datasheet Extract

Progesterone Receptor antibody [hpra 2 + hpra 3]
BackgroundThe human Progesterone Receptor (PgR) is a member of the steroid family of nuclear receptors. PgR is found as a 120 kDa protein (Form B) or a 94 kDa protein (Form A) due to the use of alternative translation initiation sites. In its inactive state, PgR forms a multiprotein complex which includes heat shock proteins and immunophins. Upon binding of progesterone hormone to its receptor, there is a conformational change that allows dimerization and binding of the receptor to progesterone response elements (PRE) sequences, resulting in activated transcription. When bound to DNA, PgR can positively or negatively regulate gene transcription through the recruitment of coactivator (e.g. SRC 1) or corepressor (e.g. NCoR) proteins. PgR is phosphorylated on multiple serine residues through distinct groups of sites regulated by hormone and different kinases. Progesterone receptor is present in the CNS in monoenzymatic aromatic L-amino acid decarboxylase (AADC) containing cells of the preoptic area and also in neurons expressing both AADC and tyrosine hydroxylase (TH) in the arcuate nucleus.
ImmunogenBALB/C mice were injected with progesterone receptor from human endometrial carcinoma (EnCa 101) grown in athymic mice.
Swiss Num.: P06401
Format
Purification: IgG fraction
Purity: IgG fraction
BufferSystem: Preservative: Sodium Azide
ApplicationsIHC-P
SpecificityHuman - Not yet tested in other species
StorageKeep as concentrated solution, aliquot and store at 4

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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