GTX15456 Presenilin 1 / PS1 / PSEN1 antibody
see related secondary antibodiessee all 30 Presenilin 1 / PS1 / PSEN1 products
200 µg / no delivery possible
Quick Overview
Mouse anti Presenilin 1 / PS1 / PSEN1 APS 11
Synonyms
Presenilin-1, PS-1, Protein S182, AD3, PSNL1, , Alzheimer disease 3
Product review
Please read our product review about Presenilin 1 / PS1 / PSEN1 : Antibody Panel to Presenilin 1 + 2.
Product Description
Mouse anti Presenilin 1 / PS1 / PSEN1 APS 11, Presentation: Purified. Product is tested for Enzyme Immunoassay ( E ), Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Enzyme Immunoassay ( E ), Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ), Monkey ( Mky ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | APS 11 |
| Catalog Number | GTX15456 |
| Swiss Prot. No. | P49768 |
| Quantity | 200 µg |
| Price | no delivery possible |
| Delivery | Europe only |
| Manufacturer | GeneTex Inc. |
| Datasheet |  http://www.genetex.com/co ... |
Datasheet Extract
| Presenilin 1 antibody [APS 11] | |
| Concentration | 1 mg/ml |
| Background | Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2). Presenilins form the catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Evidence suggests cleavage of APP by gamma-secretase and the production of Abeta (42 aa) is likely to play a important or casual role in the development of Alzheimer's disease. |
| Immunogen | Synthetic peptide: HLSNTVRSQNDNRE, corresponding to amino acids 21-34 of Human Presenilin 1 with N-terminally added cysteine. Swiss Num.: P49768 |
| Format | Purification: Protein G purified Purity: Protein G purified BufferSystem: Preservative: 0.05% Sodium Azide; Constituents: PBS, 1mg/ml BSA |
| Applications | ELISA, IF, IHC-P, WB |
| Specificity | Cross-reacts with Human, Mouse and Rat. Expected to cross-react with Cow (92% identity with immunogen), Cynomolgus Monkey (100% identity with immunogen) and Dog (92% identity with immunogen) due to sequence homology. Not yet tested in other species. |
| Storage | Aliquot and store at -80 |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'GTX15456 Presenilin 1 / PS1 / PSEN1 '.
