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DM327  XRCC6 / Ku70 / CTC75 antibody

see related secondary antibodies
see all 28 XRCC6 / Ku70 / CTC75 products
1 ml / US$ 535
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com

Quick Overview

Mouse anti XRCC6 / Ku70 / CTC75 S5C11

Synonyms

DNA-repair protein XRCC6, TLAA, CTCBF, XRCC-6, , ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II 70 kDa subunit, Lupus Ku autoantigen protein p70, 70 kDa subunit of Ku antigen, Thyroid-lupus autoantigen, CTC box-binding factor 75 kDa subunit, Ku 70, XRCC-6

Product review
Please read our product review about XRCC6 / Ku70 / CTC75 : Antibodies to XRCC Proteins.

Product Description

Mouse anti XRCC6 / Ku70 / CTC75 S5C11, Presentation: Purified. Product is tested for Immunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )

Properties

ApplicationsImmunofluorescence ( IF ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
ReactivityHuman ( Hu ), Monkey ( Mky )
PresentationPurified
HostMouse
IsotypeIgG1
CloneS5C11
Catalog NumberDM327
Swiss Prot. No.P12956
Quantity1 ml
PriceUS$ 535
DeliveryWorldwide
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
DM327.pdf

Datasheet Extract

BackgroundKu autoantigen is a heterodimer of p70 kD (p70) and 80 kD (p80) proteins. The p70/p80 dimer is important for the function of a 460 kD DNA-dependant protein kinas that phosphorylates certain transcription factors, including sp1, Oct-1, p53 and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis.
ImmunogenBALB/C mice were injected with human placental extract (PSE1-PL).
Swiss Num.: P12956
Format
State: Liquid Ig fraction containing Sodium Azide as preservative.
ApplicationsImmunoprecipitation.
Immunofluorescence.
Western Blot.
Immunohistochemistry on paraffin embedded sections: 1/50-1/100 dilution in an ABC method (30 minutes at RT).
Recommended Positive Control: Tonsil.
SpecificityThis antibody reacts with a 70 kD protein known as Ku (p70).
Cellular Localization: Nuclear.
Species: Human, Monkey.
StorageStore the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Ajmani et al. J Exptl Med 181 (6): 2049, 1995.
2. Knuth et al. J Biol Chem 265: 17911, 1990.

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

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