BM6044P Cardiotin antibody
see related secondary antibodiessee all 9 Cardiotin products
0.1 mg / please contact our distributor
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti Cardiotin SR-2
Product review
Please read our product review about Cardiotin: Antibodies to Cardiotin.
Product Description
Mouse anti Cardiotin SR-2, Presentation: Purified. Product is tested for Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Por ( Por ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgM |
| Clone | SR-2 |
| Catalog Number | BM6044P |
| Quantity | 0.1 mg |
| Price | please contact our distributor |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  BM6044P.pdf |
Datasheet Extract
| Monoclonal Antibody to Cardiotin | |
| Concentration | 1 mg/ml |
| Background | Cardiotin is a high molecular weight protein complex (300 kDa) located in the mitochondria of cardiomyocytes and skeletal muscle. The cardiotin structure exists of subunits of 60 kDa and 100 kDa, probably in a tetrameric configuration. Both subunits contain the same amino- erminal 14 amino-acid sequence, showing high homology to human skeletal muscle α-actinin. During cardiac contractile dysfunction and myocard cell differentiation, the cardiotin distribution is affected. Compared to other structural proteins, cardiotin is one of the first to respond to insults (ischemia, fibrillation) that influence the functional status of cardiomyocytes. |
| Immunogen | 100 kDa cardiotin subunit |
| Format | BufferSystem: PBS containing 0.09 % sodium azide |
| Applications | Immunohistochemistry on frozen and paraffin-embedded tissue (1:25 - 1:100, with avidinbiotinylated horseradish peroxidase complex (ABC) as detection reagent).
Immunoblotting (1:50 - 1:500, reacts with the 300 kDa cardiotin protein complex and its 100 kDa and 60 kDa subunits). |
| Specificity | SR-2 reacts with cardiotin, a mitochondrionassociated protein, which is present in cardiomyocytes and skeletal muscle. SR-2 reacts with cardiomyocytes, skeletal muscle, stromal and epithelial cells as well in vivo as in vitro. Species: Human, swine. |
| Storage | Store at 2 - 8 °C, or in small aliquots at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Schaart, G., Moens, L., Endert, J. M., and
Ramaekers, F. C. (1997). Biochemical characterization of cardiotin, a sarcoplasmic reticulum associated protein, FEBS Lett 403, 168-72. |
10 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1349B | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | Biotin | 2 mg / 230,00 € | |||||
| R1349F | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | FITC | 2 mg / 210,00 € | |||||
| R1349T | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | TRITC | 2 mg / 210,00 € | |||||
| R1349TR | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | Texas Red | 2 mg / 230,00 € | |||||
| R1349HRP | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | HRP | 2 mg / 240,00 € | |||||
| R1349AP | Mouse IgA + IgG + IgM (H&L) | ||||||
| Goat | AP | 1 mg / 260,00 € | |||||
| SP1018F | Mouse IgM mu chain | ||||||
| Goat | FITC | Ms | 1 mg / 250,00 € | ||||
| SP1018R | Mouse IgM mu chain | ||||||
| Goat | PE | Ms | 0.1 mg / 350,00 € | ||||
| SP1018HRP | Mouse IgM mu chain | ||||||
| Goat | HRP | Ms | 1 mg / 260,00 € | ||||
| SP1018AP | Mouse IgM mu chain | ||||||
| Goat | AP | Ms | 0.8 mg / 300,00 € | ||||
Click here to see all secondary antibodies for 'BM6044P Cardiotin'.
