BM5058 ABCB1 / MDR1 antibody
see related secondary antibodiessee all 15 ABCB1 / MDR1 products
0.5 ml / US$ 535
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti ABCB1 / MDR1 JSB-1
Synonyms
Multidrug resistance protein 1 P-glycoprotein 1 CD243 PGY1
Product Description
Mouse anti ABCB1 / MDR1 JSB-1, Presentation: Supernatant. Product is tested for Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Paraffin Sections ( P ), Westernblot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Supernatant |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | JSB-1 |
| Catalog Number | BM5058 |
| Quantity | 0.5 ml |
| Price | US$ 535 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  BM5058.pdf |
Datasheet Extract
| Monoclonal Antibody to P-Glycoprotein (P-GP) | |
| Concentration | approx. 250 µg/ml |
| Immunogen | Human P-Glycoprotein |
| Format | State: Liquid BufferSystem: Cell culture supernatant containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative |
| Applications | Western blotting.
Immunocytochemistry. Flow cytometry (1/10, requires cell permeabilization). Immunohistochemistry on frozen and paraffin embedded sections (1/20; Paraffin sections require B-5 fixation and microwave pre-treatment). Dilute with PBS containing 1% BSA and 0.09% Sodium Azide. |
| Specificity | The antibody reacts with a conserved cytoplasmic epitope of the plasma membrane-associated P-Glycoprotein, a 170 kDa multidrug resistance related protein. It detects P-Glycoprotein overexpression in human tumor cells of all different histogenetic origins. Species: Human, chinese hamster, neagative with mouse and rat |
| Storage | Store the antibody at 2-8°C for one month or at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch. |
| References | Scheper, R.J. et al.: Monoclonal antibody JSB-1 detects a highly conserved epitope on the P-glycoprotein associated with Multi-Drug-Resistance. Int. J. Cancer 42:389 (1988).
Dalton WS, TM Grogan, PS Meltzer, RJ Scheper, BGM Durie, CW Taylor, TP Miller, and SE Salmon. Drug-Resistance in Multiple Myeloma and Non-Hodgkins's Lymphoma: Detection of P-Glycoprotein and Potential Circumvention by Addition of Verapamil to Chemotherapy. J Clin Oncology, Vol 7, 4:415-424 |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'BM5058 ABCB1 / MDR1'.
