BM5057 ABCC1 / MRP1 antibody
see related secondary antibodiessee all 23 ABCC1 / MRP1 products
0.5 ml / US$ 585
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Mouse anti ABCC1 / MRP1 MRPm6
Synonyms
Multidrug resistance-associated protein 1, LTC4 transporter, ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter
Product Description
Mouse anti ABCC1 / MRP1 MRPm6, Presentation: Supernatant. Product is tested for Frozen sections ( C ), Flow cytometry ( F ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB )
Properties
| Applications | Frozen sections ( C ), Flow cytometry ( F ), Paraffin Sections ( P ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Supernatant |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | MRPm6 |
| Catalog Number | BM5057 |
| Swiss Prot. No. | P33527 |
| Quantity | 0.5 ml |
| Price | US$ 585 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  BM5057.pdf |
Datasheet Extract
| Alternate names | MRP1, ABCC, GS-X, ABC29 |
| Concentration | concentration approx. 250 µg/ml |
| Background | MRP1 (also known as ABCC, GS-X, ABC29) functions as a multispecific organic anion transporter, with (oxidized) glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. It also transports drugs and other hydrophobic compounds in presence of glutathione. |
| Immunogen | Bacterial fusion protein containing a 170 aa segment in the carboxy-terminal end and part of the carboxy-proximal nucleotide binding domain of MRP1 Swiss Num.: P33527 AA Sequence: 1294 - 1531 |
| Format | State: Liquid Culture supernatant BufferSystem: PBS with 1% BSA and 0.1% Na-Azide |
| Applications | Immunostaining of cell suspensions and cytospin preparations.
Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections (after microwave treatment): 0.01M citrate buffer; 3x 3min at 100°C. Flow cytometry: cell permeabilization required with 10% lyzing solution. Western Blot: 180 - 195 kD glycoprotein. Working Dilution: 1:20 - 1:50 |
| Specificity | Mab MRPm6 reacts with an internal epitope of MRP1 (aa 1511-1520), a 1531 aa protein, overexpressed in various human non-Pglycoprotein MDR tumor cell lines. Does not cross-react with human P-glycoprotein, MDR3 P-glycoprotein or human cMOAT / MRP2 to MRP5. Species: Human. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Flens M et al. Am J Pathol 148 1237-1247(1996)
2. Nooter et al. Ann Oncol 7, 75-81(1996) 3. Schadendorf et al. Am J Pathol 147, 1545-1552 (1995) 4. Flens MJ et al. Cancer Research 54:4557-4563 (1994) 5. Zaman et al. Proc Natl Acad Sci USA 91:8822-8826 (1994) 6. Cole SPC et al. Science 258:1650-1654 (1992) |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'BM5057 ABCC1 / MRP1'.
