AP00886PU-N T-box Transcription Factor 22 (T-box22, TBX22) antibody
see related secondary antibodies
0.1 mg / US$ 425
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti T-box Transcription Factor 22 (T-box22, TBX22)
Product Description
Rabbit anti T-box Transcription Factor 22 (T-box22, TBX22) , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | AP00886PU-N |
| Quantity | 0.1 mg |
| Price | US$ 425 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00886PU-N.pdf |
Datasheet Extract
| Concentration | 1,0 mg/ml |
| Background | T-box transcription factors contain a novel type of DNA-binding domain, the T-box domain, which are encoded by an ancient gene family. 12 human T-box genes have been isolated. Mutations in T-box 22 (TBX22) have been associated with the inherited X-linked disorder cleft palate with ankyloglossia. There is evidence that TBX22 seems to play a major role in human palatogenesis. In mouse embryos, TBX22 is expressed in distinct areas of the head, namely the mesenchyme of the interior nasal septum, the posterior palatal shelf before fusion, the attachment of the tongue and mesenchymal cells surrounding the eye anlage. |
| Immunogen | KLH-conjugated synthetic peptide comprised of amino acids 507 - 520 of the human T-box 22 (TBX22) protein |
| Format | State: Liquid purified Ig Purification: Protein G chromatography BufferSystem: PBS, pH 7.2 containing 0.02% Sodium azide |
| Applications | Western blot: 1:500 - 1:1,000. |
| Specificity | This antibody reacts to T-box Transcription Factor 22. Species: Human. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Braybrook, C., et al., (2002), Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patientsâ??, Hum. Mol. Genet., 11(22), 2793 - 2804.
2. Aldred, M.A., (2001), Cleft lip and palate: new genetic clues, Trends Mol. Med., 7(12): 539 - 540. 3. Braybrook, C., et al., (2001), The T-box transcription factor gene TBX22 is mutated in X-linked cleft palate and ankyloglossia, Nat. Genet., 29(2): 179 - 183. 4. Laugier-Anfossi, F. and Villard, L., (2000), Molecular characterization of a new human T-box gene (TBX22) located in xq21.1 encoding a protein containing a truncated T-domain, Gene, 255(2): 289 - 296. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
