AP00885PU-N T-box Transcription Factor 21 (T-box21, TBX21) antibody
see related secondary antibodies
0.1 mg / US$ 425
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti T-box Transcription Factor 21 (T-box21, TBX21)
Product Description
Rabbit anti T-box Transcription Factor 21 (T-box21, TBX21) , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | AP00885PU-N |
| Quantity | 0.1 mg |
| Price | US$ 425 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00885PU-N.pdf |
Datasheet Extract
| Concentration | 1,0 mg/ml |
| Background | T-box transcription factors contain a novel type of DNA-binding domain, the T-box domain, which are encoded by an ancient gene family. 12 human T-box genes have been isolated. T-box 21 (TBX21) is the human ortholog of mouse Tbx21/Tbet gene and studies in mice have shown that Tbx21 is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of human TBX21 also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for TBX21 in initiating Th1 lineage development from naive Th precursor cells. |
| Immunogen | KLH-conjugated synthetic peptide comprised of amino acids 519 - 535 of the human T-box 21 (TBX21) protein |
| Format | State: Liquid purified Ig Purification: Protein G chromatography BufferSystem: PBS, pH 7.2 containing 0.02% Sodium azide |
| Applications | Western blot: 1:500 - 1:1,000. |
| Specificity | This antibody reacts to T-box Transcription Factor 21. Species: Human. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Faedo, A., et al., (2002), Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis, Mech. Dev., 116(1 - 2): 157 - 160.
2. Zhang, W.X. and Yang, S.Y., (2000), Cloning and characterization of a new member of the T-box gene family, Genomics, 70(1): 41 - 48. 3. Szabo, S.J., et al., (2000), A novel transcription factor, T-bet, directs Th1 lineage commitment, Cell, |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
