AP00882PU-N T-box Transcription Factor 19 (T-box19, TBX19) antibody
see related secondary antibodies
0.1 mg / US$ 425
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti T-box Transcription Factor 19 (T-box19, TBX19)
Product Description
Rabbit anti T-box Transcription Factor 19 (T-box19, TBX19) , Presentation: Purified. Product is tested for Western blot / Immunoblot ( WB )
Properties
| Applications | Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Rabbit |
| Catalog Number | AP00882PU-N |
| Quantity | 0.1 mg |
| Price | US$ 425 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00882PU-N.pdf |
Datasheet Extract
| Background | T-box transcription factors contain a novel type of DNA-binding domain, the T-box domain, which are encoded by an ancient gene family. 12 human T-box genes have been isolated. T-box 19 (TBX19) is the human ortholog of mouse Tbx19/Tpit gene and studies in mice have show that Tpit is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human TBX19 were found in patients with isolated deficiency of pituitary POMC-derived ACTH (adrenocorticotropic hormone deficiency), suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. |
| Immunogen | KLH-conjugated synthetic peptide comprised of amino acids 328â??344 of the human T-box 19 (TBX19) protein |
| Format | State: Liquid purified Ig Purification: Protein G chromatography BufferSystem: PBS, pH 7.2 containing 0.02% Sodium azide |
| Applications | Western blot: 1:500 - 1:1,000. |
| Specificity | This antibody reacts with T-box 19, amino acids 328 - 344. Species: Human. |
| Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| References | 1. Maira, M., et al., (2003), The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action, J. Biol. Chem., 278(47): 46523 - 46532.
2. Pulichino, A.M., et al., (2003), Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency, Genes Dev., 17(6), 711 - 716. 3. Asteria, C., (2002), T-box and isolated ACTH deficiency, Eur. J. Endocrinol., 146(4): 463 - 465. 4. Lamolet, B., et al., (2001), A pituitary cell-restricted T box factor, Tpit, activates POMC transcription in cooperation with Pitx homeoproteins, Cell, 104(6): 849 - 859. 5. Yi, C.H., et al., (1999), Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18 and TBX19, Genomics, 55(1), 10 - 20. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
