AP00006PU-N Caspase-1 / CASP-1 antibody
see related secondary antibodiessee all 29 Caspase-1 / CASP-1 products
0.1 mg / US$ 405
NOVUS BIOLOGICALS
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
PO Box 802 Littleton, CO 80160, USA
E-Mail: novus@novus-biologicals.com
Homepage: http://www.novus-biologicals.com
Quick Overview
Rabbit anti Caspase-1 / CASP-1
Synonyms
CASP1, ICE, p45, IL-1BC, IL1BC, IL1BCE, , Caspase 1, Caspase1, CASP 1, Interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, IL-1 beta-converting enzyme
Product review
Please read our product review about Caspase-1 / CASP-1: Antibodies to Caspase Family.
Product Description
Rabbit anti Caspase-1 / CASP-1 , Presentation: Aff - Purified. Product is tested for Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB )
Properties
| Applications | Immunofluorescence ( IF ), Immunoprecipitation ( IP ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Mouse ( Ms ), Rat ( Rt ) |
| Presentation | Aff - Purified |
| Host | Rabbit |
| Catalog Number | AP00006PU-N |
| Swiss Prot. No. | P29466 |
| Quantity | 0.1 mg |
| Price | US$ 405 |
| Delivery | Worldwide |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AP00006PU-N.pdf |
Datasheet Extract
| Concentration | 0.2 mg/ml |
| Background | Caspase family of cysteine proteases has been shown to play a key role in apoptosis. Caspase-1 (ICE, interleukin-1β-converting enzyme) is the mammalian caspase responsible for the proteolytic conversion of the proforms of interleukin-1β and IL-18 into active cytokines. Like other caspases, Caspase-1 itself is synthesized as a pro-enzyme that is cleaved during activation into a large (20 kDa) and small (10 kDa) subunits. The cellular role of caspase-1 appears limited to cytokine activation as they do not have obvious roles in apoptosis. |
| Immunogen | Synthetic peptide surrounding amino acid 132 of human caspase-1 Swiss Num.: P29466 |
| Format | State: Liquid purified Ig Purification: Immunoaffinity BufferSystem: PBS, pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
| Applications | Western Blot: 0.5-4 μg/ml.
Immunoprecipitation: 4-8 μg/ml. Immunofluorescence: 10-20 μg/ml. |
| Specificity | The immunoaffinity purified antibody recognizes 45 kDa procaspase-1 and the 20 kDa cleaved product. Species: Human, Mouse, Rat. |
| Add. Information | Blocking peptide (AP00006CP-N) is available separately. |
| Storage | Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C.
Avoid repeated freezing and thawing. Shelf life: one year from despatch. |
| Pictures | Western blot analysis of Caspase-1 expression in Rat liver tissue lysate. |
12 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1364B | Rabbit IgG (H&L) | ||||||
| Goat | Biotin | 2 mg / US$ 295 | |||||
| R1364F | Rabbit IgG (H&L) | ||||||
| Goat | FITC | 2 mg / US$ 285 | |||||
| R1364T | Rabbit IgG (H&L) | ||||||
| Goat | TRITC | 2 mg / US$ 285 | |||||
| R1364TR | Rabbit IgG (H&L) | ||||||
| Goat | Texas Red | 2 mg / US$ 295 | |||||
| R1364HRP | Rabbit IgG (H&L) | ||||||
| Goat | HRP | 2 mg / US$ 295 | |||||
| R1364AP | Rabbit IgG (H&L) | ||||||
| Goat | AP | 1 mg / US$ 325 | |||||
| R1458C2 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1458C3 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1458C35 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1458C5 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1458C55 | Rabbit IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1427R | Rabbit IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'AP00006PU-N Caspase-1 / CASP-1'.
