AM00605PU-N CD1a antibody
see related secondary antibodiessee all 47 CD1a products
0.1 mg / no delivery possible
please contact the manufacturer
Quick Overview
Mouse anti CD1a O10
Synonyms
Dendritic cell marker T-cell surface glycoprotein CD1A, T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen
Product review
Please read our product review about CD1a: Antibodies for Characterization of Dendritic Cells.
Product Description
Mouse anti CD1a O10, Presentation: Purified. Product is tested for Paraffin Sections ( P )
Properties
| Applications | Paraffin Sections ( P ) |
| Reactivity | Human ( Hu ) |
| Presentation | Purified |
| Host | Mouse |
| Isotype | IgG1 |
| Clone | O10 |
| Catalog Number | AM00605PU-N |
| Swiss Prot. No. | P06126 |
| Quantity | 0.1 mg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view  AM00605PU-N.pdf |
Datasheet Extract
| Monoclonal Antibody to CD1a | |
| Concentration | 0.2 mg/ml |
| Background | At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes. CD1 proteins have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. |
| Immunogen | Swiss Num.: P06126 |
| Format | State: Liquid Ig fraction Purification: Protein G chromatography BufferSystem: 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide |
| Applications | Immunohistology (Formalin/paraffin): 1:50-1:100 for 30 min at RT; staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.
Positive Control: Tonsil. |
| Specificity | This antibody detects CD1a at 49 kDa.
It detects cortical thymocytes, Langerhans cells in epidermis, dendritic cells of dermis and Langherhans cells of mucosa of tonsil. It may also detect small focal groups of lymphocytes outside the germinal centers of tonsil indicating a crossreaction with CD1b. This antibody is useful in the characterization of leukaemias and lymphomas. Species: Human. |
| Add. Information | Cellular Localization: Cell membrane and cytoplasm |
| Storage | Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| References | 1. Aractingi S, et al. J Clin Pathol. 50: 305-309 (1997).
2. Bobryshev Y V, et al. Pathol Res Pract. 192: 462-467 (1996). 3. Mazal P R, et al Clin Neuropathol. 15: 87-91 (1996). |
| Pictures | Formalin-fixed, paraffin-embedded human tonsil stained with CD1a (AM00605PU-N) using peroxidase-conjugate and AEC chromogen. Note membrane staining of interdigitating cells of stratified squamous epithelium of tonsil. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1253B | Mouse IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 305 | |||||
| R1253F | Mouse IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1253T | Mouse IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1253TR | Mouse IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1253HRP | Mouse IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1253AP | Mouse IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 325 | |||||
| R1457C2 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1457C3 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1457C35 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1457C5 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1457C55 | Mouse IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1405R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1403R | Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins | ||||||
| Rabbit | PE | 1 ml / US$ 455 | |||||
| R1455R | Mouse IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'AM00605PU-N CD1a'.
