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Formalin-fixed, paraffin-embedded human skin stained with CD1a (AM00604SU-N) using peroxidase-conjugate and AEC chromogen. Note staining of Langerhans cells in epidermis.

 

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AM00604SU-N  CD1a antibody

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see all 53 CD1a products
0.5 ml / no delivery possible
please contact the manufacturer

Quick Overview

Mouse anti CD1a MTB1

Synonyms

T-cell surface antigen T6/Leu-6, hTa1 thymocyte antigen, CD1, , T-cell surface glycoprotein CD1A, Dendritic cell marker, Epidermal dendritic cell marker CD1a, Thymocyte Antigen CD1A

Product review
Please read our product review about CD1a: Antibodies for Characterization of Dendritic Cells.

Product Description

Mouse anti CD1a MTB1, Presentation: Supernatant. Product is tested for Paraffin Sections ( P )

Properties

ApplicationsParaffin Sections ( P )
ReactivityHuman ( Hu )
PresentationSupernatant
HostMouse
IsotypeIgG1
CloneMTB1
Catalog NumberAM00604SU-N
Swiss Prot. No.P06126
Quantity0.5 ml
Priceno delivery possible
DeliveryNot USA/Canada
ManufacturerAcris Antibodies GmbH
Datasheetview PDF-Download
AM00604SU-N.pdf

Datasheet Extract

BackgroundAt least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes. CD1 proteins have been demonstrated to restrict T-cell response to nonpeptide lipid and glycolipid antigens and play a role in non-classical antigen presentation.
ImmunogenRecombinant protein corresponding to the full length external domain of CD1a
Swiss Num.: P06126
Format
State: Liquid tissue culture supernatant
BufferSystem: 0.09 % sodium azide
ApplicationsImmunohistology (Formalin/paraffin): at 1:15 for 30 min at RT; staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1 mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.
Positive Control: Thymus.
SpecificityThis antibody detects CD1a.
It detects cortical thymocytes, Langerhans cells in epidermis, dendritic cells of dermis and Langherhans cells of mucosa of tonsil. It may also detect small focal groups of lymphocytes outside the germinal centers of tonsil indicating a crossreaction with CD1b. This antibody is useful in the characterization of leukaemias and lymphomas.
Species: Human.
Add. InformationCellular Localization: Cell membrane and cytoplasm
StorageStore the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
References1. Aractingi S, et al. J Clin Pathol. 50: 305-309 (1997).
2. Bobryshev Y V, et al. Pathol Res Pract. 192: 462-467 (1996).
3. Mazal P R, et al Clin Neuropathol. 15: 87-91 (1996).
PicturesFormalin-fixed, paraffin-embedded human skin stained with CD1a (AM00604SU-N) using peroxidase-conjugate and AEC chromogen. Note staining of Langerhans cells in epidermis.

14 Secondary Antibodies

Catalog No.Name / HostPresentationReactivity 
R1253B Mouse IgG (H&L)  
  Rabbit Biotin   2 mg / US$ 305
   
R1253F Mouse IgG (H&L)  
  Rabbit FITC   2 mg / US$ 285
   
R1253T Mouse IgG (H&L)  
  Rabbit TRITC   2 mg / US$ 285
   
R1253TR Mouse IgG (H&L)  
  Rabbit Texas Red   2 mg / US$ 295
   
R1253HRP Mouse IgG (H&L)  
  Rabbit HRP   2 mg / US$ 315
   
R1253AP Mouse IgG (H&L)  
  Rabbit AP   1 mg / US$ 325
   
R1457C2 Mouse IgG (H&L) multi-species ads.  
  Goat Cy2   1 mg / US$ 445
   
R1457C3 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3   1 mg / US$ 445
   
R1457C35 Mouse IgG (H&L) multi-species ads.  
  Goat Cy3.5   1 mg / US$ 445
   
R1457C5 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5   1 mg / US$ 445
   
R1457C55 Mouse IgG (H&L) multi-species ads.  
  Goat Cy5.5   1 mg / US$ 445
   
R1405R Mouse IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh  
  Goat PE   1 ml / US$ 455
   
R1403R Mouse IgG (H&L) F(ab')2 Fragment ads. to Hu serum proteins  
  Rabbit PE   1 ml / US$ 455
   
R1455R Mouse IgG (H&L) F(ab')2 Fragment multi-species ads.  
  Donkey PE   1 ml / US$ 455
   

Click here to see all secondary antibodies for 'AM00604SU-N CD1a'.