AM00373PU-N Estrogen Receptor alpha / ESR1 antibody
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0.1 mg / no delivery possible
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Quick Overview
Rat anti Estrogen Receptor alpha / ESR1 H222
Synonyms
ER-alpha, Estradiol receptor, ESR, NR3A1, , Nuclear receptor subfamily 3 group A member 1, Estrogen receptor, ER alpha, Estrogen receptor 1, Major ORF
Product review
Please read our product review about Estrogen Receptor alpha / ESR1 : Antibodies to Estrogen Receptors and Estrogen-Related Receptors.
Product Description
Rat anti Estrogen Receptor alpha / ESR1 H222, Presentation: Purified. Product is tested for ELISA (detection) ( E(detection) ), Western blot / Immunoblot ( WB )
Properties
| Applications | ELISA (detection) ( E(detection) ), Western blot / Immunoblot ( WB ) |
| Reactivity | Human ( Hu ), Rat ( Rt ) |
| Presentation | Purified |
| Host | Rat |
| Isotype | IgG1 |
| Clone | H222 |
| Catalog Number | AM00373PU-N |
| Swiss Prot. No. | P03372 |
| Quantity | 0.1 mg |
| Price | no delivery possible |
| Delivery | Not USA/Canada |
| Manufacturer | Acris Antibodies GmbH |
| Datasheet | view AM00373PU-N.pdf |
Datasheet Extract
| Concentration | 0.2 mg/ml |
| Background | ER protein exhibits six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. It is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors may improve response to anti-estrogen therapy. |
| Immunogen | Estrogen receptor purified from MCF-7 cells. Swiss Num.: P03372 Remarks: Mol. Wt. of Antigen: 67 kDa |
| Format | State: Liquid ascites fluid Purification: Protein G chromatography BufferSystem: 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide. |
| Applications | ELISA: use as a reporter Ab.
Western Blotting: 1-2 µg/ml for 2 hrs at RT. Positive Control: MCF-7 cells. Breast Carcinoma. |
| Specificity | This antibody detects Estrogen Receptor. Species: Human and Rat. |
| Add. Information | Shows broad species reactivity.
Cellular Localization: Nuclear. |
| Storage | Store the antibody at 2 - 8 °C up to one month or in aliquots at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. |
| References | 1. Green G, et al. (1984) J. Steroid Biochem. 20: 51-56.
2. Katzenellenbogen B, et al. (1987) Biochemistry 26: 2364-2373. 3. Miller R T, Hapke M R, Greene G L. (1993) Cancer 71:3541-3546. |
14 Secondary Antibodies
| Catalog No. | Name / Host | Presentation | Reactivity | ||||
|---|---|---|---|---|---|---|---|
| R1371B | Rat IgG (H&L) | ||||||
| Rabbit | Biotin | 2 mg / US$ 295 | |||||
| R1371F | Rat IgG (H&L) | ||||||
| Rabbit | FITC | 2 mg / US$ 285 | |||||
| R1371T | Rat IgG (H&L) | ||||||
| Rabbit | TRITC | 2 mg / US$ 285 | |||||
| R1371TR | Rat IgG (H&L) | ||||||
| Rabbit | Texas Red | 2 mg / US$ 295 | |||||
| R1371HRP | Rat IgG (H&L) | ||||||
| Rabbit | HRP | 2 mg / US$ 315 | |||||
| R1371AP | Rat IgG (H&L) | ||||||
| Rabbit | AP | 1 mg / US$ 335 | |||||
| R1439C2 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy2 | 1 mg / US$ 445 | |||||
| R1439C3 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3 | 1 mg / US$ 445 | |||||
| R1439C35 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy3.5 | 1 mg / US$ 445 | |||||
| R1439C5 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5 | 1 mg / US$ 445 | |||||
| R1439C55 | Rat IgG (H&L) multi-species ads. | ||||||
| Goat | Cy5.5 | 1 mg / US$ 445 | |||||
| R1413R | Rat IgG (H&L) F(ab')2 Fragment ads. to Bov, Eq, Hu, Ms, Rb, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
| R1428R | Rat IgG (H&L) F(ab')2 Fragment multi-species ads. | ||||||
| Donkey | PE | 1 ml / US$ 455 | |||||
| R1415R | Rat IgG F(ab')2 F(ab')2 Fragment ads. to Bov, Eq, Hu, Rb, Rt, Sh | ||||||
| Goat | PE | 1 ml / US$ 455 | |||||
Click here to see all secondary antibodies for 'AM00373PU-N Estrogen Receptor alpha / ESR1 '.

